Extrauterine growth restriction: Is it preventable?

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Extrauterine growth restriction: is it preventable?

Longstanding recommendations by the American Academy of Pediatrics, the Canadian Paediatrics Society, and the European Society of Paediatric Gastroenterology, Hepatology, and Nutrition state that the nutritional management of preterm infants, especially of extremely preterm (EPT) infants, should support growth at a rate that approximates the rate of intrauterine growth. However, extrauterine gr...

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EDITORIAL Extrauterine growth restriction : is it preventable ? ,

Longstanding recommendations by the American Academy of Pediatrics,1,2 the Canadian Paediatrics Society,3 and the European Society of Paediatric Gastroenterology, Hepatology, and Nutrition4,5 state that the nutritional management of preterm infants, especially of extremely preterm (EPT) infants, should support growth at a rate that approximates the rate of intrauterine growth. However, extraute...

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Epigenetics of Notch1 regulation in pulmonary microvascular rarefaction following extrauterine growth restriction

BACKGROUND Extrauterine growth restriction (EUGR) plays an important role in the developmental origin of adult cardiovascular diseases. In an EUGR rat model, we reported an elevated pulmonary arterial pressure in adults and genome-wide epigenetic modifications in pulmonary vascular endothelial cells (PVECs). However, the underlying mechanism of the early nutritional insult that results in pulmo...

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Extrauterine growth restriction in preterm infants: importance of optimizing nutrition in neonatal intensive care units.

Extrauterine growth restriction in preterm infants secondary to suboptimal nutrition is a major problem in neonatal intensive care units. Evidence is emerging that early growth deficits have long-term adverse effects, including short stature and poor neurodevelopmental outcomes. The parenteral route of feeding is essential to maintain nutritional integrity before successful transition to the en...

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ژورنال

عنوان ژورنال: Jornal de Pediatria (Versão em Português)

سال: 2014

ISSN: 2255-5536

DOI: 10.1016/j.jpedp.2013.10.003